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Recombinant Human TNF RII/TNFRSF1B Protein

CAS number:unknown    molecular formula:

overview

compound introduction

Purity >95% SDS-PAGE. Function Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Specs

Chinese alias肿瘤坏死因子受体超家族成员1B | 重组人 TNF RII/TNFRSF1B 蛋白
English aliasCD120b antigen | CD120b | Etanercept | p75 TNF receptor | p75TBPII | p75TNFR | soluble TNFR1B variant 1 | TNF RII | TNFBRp80 TNF-alpha receptor | TNF-R2 | TNFR2TNFR1B | TNF-R75 | TNFR80 | TNFRII | TNF-RII | TNF-R-II | TNFR-II | TNFRSF1B | tumor necrosis f
CAS numberunknownmolecular formula
molecular weight-Exact mass无载体
PSA-logp-

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