Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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Recombinant Mouse IL-12/IL-23 p40 Monomer Protein
CAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | 重组小鼠IL-12/IL-23 p40蛋白 | 重组小鼠白介素12B蛋白 | ||
| English alias | CLMF | CLMF2 | Cytotoxic lymphocyte maturation factor 40 kDa subunit | IL12 p40 | IL-12 p40 | IL-12 subunit p40 | IL12B | IL-12B | CLMF p40 | IL-12BNK cell stimulatory factor chain 2 | interleukin 12, p40 | interleukin 12B (natural killer cell stimulatory | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无载体 |
| PSA | - | logp | - |
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