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dBET23

CAS number:1957234-83-1    molecular formula:C43H45ClN8O9S

overview

compound introduction

dBET23 is a highly effective and selective PROTAC BRD4 degrader with a DC 50/5h of ~ 50 nM for BRD4 BD1 protein. In Vitro dBET23 occupies the canonical binding sites on CRBN and BRD4 BD1 for thalidomide and JQ1, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Specs

Chinese alias-
English alias-
CAS number1957234-83-1molecular formulaC43H45ClN8O9S
molecular weight885.38 g/molExact mass≥99%
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