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FKBP12 PROTAC dTAG-7

CAS number:2064175-32-0    molecular formula:C63H79N5O19

overview

compound introduction

FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional degrader. FKBP12 PROTAC dTAG-7 (dTAG-7) is a degrader of FKBP12 F36V with expression of FKBP12 F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-7 (dTAG-7) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN Form:Solid IC50& Target:FKBP12(F36V) BRD4 Cereblon

Specs

Chinese alias-
English alias-
CAS number2064175-32-0molecular formulaC63H79N5O19
molecular weight1210.32 g/molExact mass≥99%
PSA281.000 Ųlogp5.500

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