compound introduction
PROTAC BET degrader-2 is a PROTAC connected by ligands for Cereblon and BET with an IC 50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression. In Vitro PROTAC BET degrader-2 (compound 25) is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC 50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 9.6 nM (BET in the RS4,11 leukemia cell line)
