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UNC 0224

CAS number：1197196-48-7    molecular formula：C26H43N7O2

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overview

compound introduction

UNC0224 是一种有效的选择性的组蛋白甲基转移酶 G9a 抑制剂，Ki 为 2.6 nM，IC50 值为 15 nM，Kd 为 23 nM。UNC0224 还有效抑制 GLP，IC50 值为 20-58 nM。UNC0224 对 SET7/9，SET8/PreSET7，PRMT3 和 JMJD2E 无活性。

Specs

Chinese alias7-[3-(二甲基氨基)丙氧基] -2-(六氢-4-甲基-1H-1,4-二氮杂-1-基)-6-甲氧基-N-(1-甲基-4-哌啶基)-4 -喹唑啉胺
English aliasBDBM50300041 | XXB19648 | 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine | AKOS024457835 | BS-14469 | C26H43N7O2 | 7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl-1,4-diaz
CAS number1197196-48-7molecular formulaC26H43N7O2
molecular weight485.67 g/molExact mass≥98%(HPLC)
PSA69.200 Ųlogp3.400

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