Ro5-3335 是一种苯二氮化合物,能作为核心结合因子 (CBF) 白血病抑制剂。Ro5-3335 是 RUNX1-CBFβ 相互作用抑制剂,可抑制 RUNX1/CBFB 依赖性反式激活。
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Ro 5-3335
CAS number:30195-30-3 molecular formula:C13H10ClN3O
overview
compound introduction
Specs
| Chinese alias | 7-氯-5-(1H-吡咯-2-基)-1H-苯并[e][1,4]二氮杂卓-2(3H)-酮 | 7-氯-5-(1H-吡咯-2-基)-1,3-二氢-2H-1,4-苯并二氮杂卓-2-酮 | ||
| English alias | 7-Chloro-5-(2-pyrryl)-3H-1,4-benzodiazepin-2(H)-one | Ro 5-3335 | 2H-1, 7-chloro-1,3-dihydro-5-pyrrol-2-yl- | XWNMORIHKRROGW-UHFFFAOYSA-N | 7-Chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one | UNII-DLH4T68L7I | DTXSID20184270 | HY-1084 | ||
| CAS number | 30195-30-3 | molecular formula | C13H10ClN3O |
| molecular weight | 259.69 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 57.300 Ų | logp | 1.500 |
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