(Rac)-CCT 250863 盐酸盐 是一种具有选择性和可逆性的 NEK 2 抑制剂,其 IC50 值为 0.073 µM。(Rac)-CCT 250863 能诱导细胞周期停滞并有较好的抗癌细胞 (Pomalidomide 敏感/耐药) 增殖活性。(Rac)-CCT 250863 与 Pomalidomide 联用能诱导细胞凋亡,可用于联合抗癌的研究。 rac-CCT-250863 HCl is a selective and reversible inhibitor of NEK 2. rac-CCT-250863 HCl induces cell cycle arrest and has good anti-proliferative activity against cancer cells. rac-CCT-250863 HCl can be used in combination with Pomalidomide to induce apoptosis and can be used in combined anti-cancer studies. Product Describtion: Potent Nek2 inhibitor
rac-CCT-250863 HCl
CAS number:1364269-06-6(Free base) molecular formula:C24H25F3N4O2S(Free base)
overview
Specs
| Chinese alias | 4-[2-氨基-5-[4-[((二甲基氨基)甲基] -2-噻吩基] -3-吡啶基] -2-[[((2Z))-4,4,4-三氟-1-甲基-2 -丁烯-1-基]氧基]苯甲酰胺盐酸盐 | ||
| English alias | 4-[2-Amino-5-[4-[(dimethylamino)methyl]-2-thienyl]-3-pyridinyl]-2-[[(2Z)-4,4,4-trifluoro-1-methyl-2-buten-1-yl]oxy]benzamide HCl | ||
| CAS number | 1364269-06-6(Free base) | molecular formula | C24H25F3N4O2S(Free base) |
| molecular weight | 490.54(Free base) g/ | Exact mass | ≥98%(HPLC) |
| PSA | - | logp | - |
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