compound introduction
Lalistat 1 是一种有效的、选择性的、竞争性的溶酶体酸性脂肪酶抑制剂，其 IC50 为 68 nM。Lalistat 1 是流感病毒的免疫球蛋白 A1 蛋白酶 (IgA1P) 的抑制剂，对其他丝氨酸水解酶，如胰蛋白酶或内酰胺酶等影响较小。Lalistat 1 可用于 C 型尼曼氏病 (NPC) 的相关研究。
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Lalistat 1
CAS number：501104-16-1 molecular formula：C12H18N4O3S
overview
Specs
| Chinese alias | 4-(哌啶-1-基)-1,2,5-噻二唑-3-基吗啉-4-羧酸酯 | ||
| English alias | 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate | 4-morpholinecarboxylic acid, 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester | ||
| CAS number | 501104-16-1 | molecular formula | C12H18N4O3S |
| molecular weight | 298.36 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 96.000 Ų | logp | 1.400 |
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