CAS number：406208-42-2 molecular formula：C21H24N4O2
product description： A cell-permeable piperidinyl-pyridine compound that acts as a selective inhibitor of IKK-2 activity (IC50 = 8.5 and 250 nM for IKK-2 and IKK-1, respectively) with little effect towards IKK-3, Syk, and MKK4 (IC50 >20 µM). Exhibits good aqueous solubility (0.12 mg/ml in pH 7.4 isotonic buffer) and potent activity in various cellular assays in vitro (IC50
| Chinese alias | 2-氨基-6-[2-(环丙基甲氧基)-6-羟基苯基] -4-(4-哌啶基)-3-吡啶甲腈 | ||
| English alias | 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-(4-piperidinyl)-3-pyridine-carbonitrile | 2-amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-piperidin-4-ylpyridine-3-carbonitrile | 2-Amino-6-[2-(cyclopropylmethoxy)-6-oxo-2,4-cyclohexadien-1-ylidene | ||
| CAS number | 406208-42-2 | molecular formula | C21H24N4O2 |
| molecular weight | 364.44 g/mol | Exact mass | ≥97%(HPLC) |
| PSA | 104.000 Ų | logp | 2.900 |
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