介绍: V-9302 是跨膜谷氨酰胺通量的竞争性拮抗剂。V-9302 有效选择性的靶向氨基酸转运体 ASCT2 (SLC1A5),不是 ASCT1。V-9302 抑制了 HEK-293 细胞中由 ASCT2 介导的谷氨酰胺摄取 (IC50=9.6 μM)。 description: V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells
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V-9302
CAS number:1855871-76-9 molecular formula:C34H38N2O4
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| Chinese alias | - | ||
| English alias | (2S)-2-Amino-4-[bis[[2-[(3-methylphenyl)methoxy]phenyl]methyl]amino]-butanoic acid | ||
| CAS number | 1855871-76-9 | molecular formula | C34H38N2O4 |
| molecular weight | 538.68 g/mol | Exact mass | ≥98% |
| PSA | 85.000 Ų | logp | 3.700 |
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