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Hydroxy Bupropion

CAS number:357399-43-0    molecular formula:C13H18ClNO2

overview

compound introduction

羟基安非他酮是多巴胺转运抑制剂和烟碱拮抗剂安非他酮的主要代谢产物。羟基安非他酮是通过安非他酮在叔丁基上的羟基化作用而形成的,并环化成乙缩醛。这是R,R-羟基安非他酮和S,S-羟基安非他酮异构体的外消旋体。 Hydroxy Bupropion is a major metabolite of the dopamine transport inhibitor and nicotinic antagonist bupropion . Hydroxy bupropion is formed by hydroxylation of bupropion on the tert-butyl group and cyclizes to an acetal. This is a racemic preparation of the R,R-hydroxy bupropion and S,S-hydroxy bupropion isomers.

Specs

Chinese alias-
English aliasFT-0669438 | 2-(3-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLIN-2-OL | Hydroxy Bupropion | AS-6162 | 2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol | Bupropion morpholinol | BUPROPIONMORPHOLINOL | Oprea1_654095 | AKOS025149627 | FT-0669436 | SCHEMBL2599138 | D
CAS number357399-43-0molecular formulaC13H18ClNO2
molecular weight255.74 g/molExact mass≥98%
PSA41.500 Ųlogp1.900

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