A-804598 是一个 CNS 渗透,竞争性和选择性的 P2X7 受体拮抗剂,作用于小鼠,大鼠和人的 P2X7 受体,IC50s 分别是 9 nM, 10 nM 和 11 nM。
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A 804598
CAS number:1125758-85-1 molecular formula:C19H17N5
overview
compound introduction
Specs
| Chinese alias | N-氰基-N”-[((1S)-1-苯乙基] -N'-5-喹啉基-胍 | ||
| English alias | N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine | A-804598 | N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine | ||
| CAS number | 1125758-85-1 | molecular formula | C19H17N5 |
| molecular weight | 315.37 g/mol | Exact mass | - |
| PSA | 73.100 Ų | logp | 4.000 |
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