GSK319347A 是 TBK1 和 IKKε 的双重抑制剂,IC50 分别为 93 nM 和 469 nM。 GSK319347A 还抑制 IKK2,IC50 为 790 nM。 Product Describtion: GSK319347A is a dual inhibitor of TBK1 and IKKε with IC50s of 93 nM and 469 nM, respectively. GSK319347A also inhibits IKK2 with an IC50 of 790 nM.
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GSK319347A
CAS number:862812-98-4 molecular formula:C22H19N3O5S2
overview
compound introduction
Specs
| Chinese alias | 5-(5,6-二甲氧基苯并咪唑-1-基)-3-[(2-甲基磺酰基苯基)甲氧基]噻吩-2-腈 | ||
| English alias | benzimidazole-thiophene carbonitrile, 12e | CHEBI:91459 | IKK-3 Inhibitor | EINECS 211-880-2 | BRD-K51781482-001-02-1 | HMS3229F19 | LDTAHRLHGHFHKP-UHFFFAOYSA-N | AKOS002364333 | HMS3303L12 | SCHEMBL3413628 | BCP24906 | MS-28676 | HMS3305M09 | HY-14682 | | ||
| CAS number | 862812-98-4 | molecular formula | C22H19N3O5S2 |
| molecular weight | 469.53 g/mol | Exact mass | ≥97% |
| PSA | 140.000 Ų | logp | 3.800 |
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