MIND4-17 是一种有效的NRF2激活剂,可共价修饰 Keap1 的 C151 残基。MIND4-17 破坏Keap1-Nrf2结合,导致 Nrf2 蛋白稳定和核易位。MIND4-17 具有强大的抗氧化活性。
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5-Nitro-2-[[5-(phenoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]pyridine
CAS number:345989-24-4 molecular formula:C20H15N5O3S
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Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 345989-24-4 | molecular formula | C20H15N5O3S |
| molecular weight | 405.43 g/mol | Exact mass | ≥99% |
| PSA | 124.000 Ų | logp | 4.100 |
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