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5-Nitro-2-[[5-(phenoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]pyridine

CAS number:345989-24-4    molecular formula:C20H15N5O3S

overview

compound introduction

MIND4-17 是一种有效的NRF2激活剂,可共价修饰 Keap1 的 C151 残基。MIND4-17 破坏Keap1-Nrf2结合,导致 Nrf2 蛋白稳定和核易位。MIND4-17 具有强大的抗氧化活性。

Specs

Chinese alias-
English alias-
CAS number345989-24-4molecular formulaC20H15N5O3S
molecular weight405.43 g/molExact mass≥99%
PSA124.000 Ųlogp4.100

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