CAS number：1213269-23-8 molecular formula：C25H27ClN6O3
WZ4002是一种新型的，突变选择性的EGFR抑制剂，作用于EGFR(L858R)/(T790M)时IC50为2 nM/8 nM；对ERBB2磷酸化(T798I)没有抑制作用。An EGFR phosphorylation inhibitor WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50 of 2 nM/8 nM; does not inhibit ERBB2 phosphorylation (T798I). An EGFR phosphorylation inhibitor
| Chinese alias | - | ||
| English alias | NCGC00263144-02 | CCG-264847 | s1173 | WZ 4002 | N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide | BCP02515 | 2,4-Dinitrotoluene, analytical standard | NSC755927 | NSC-755927 | GTPL9176 | N,N,N-Triethy | ||
| CAS number | 1213269-23-8 | molecular formula | C25H27ClN6O3 |
| molecular weight | 494.97 g/mol | Exact mass | - |
| PSA | 91.900 Ų | logp | 4.200 |
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