compound introduction
GZD824是新型的Bcr-Abl野生型和T315I突变型抑制剂，IC50分别为0.34和0.68nM。 GZD824 is a novel bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.
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GZD824
CAS number：1257628-77-5 molecular formula：C29H27F3N6O
overview
Specs
| Chinese alias | - | ||
| English alias | MFCD26142930 | 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-(2-{1H-pyrazolo[3,4-b]pyridin-5-yl}ethynyl)benzamide | Benzamide, 4-methyl-N-(4-((4-methyl-1-piperazinyl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(1H-pyrazolo(3,4-b) | ||
| CAS number | 1257628-77-5 | molecular formula | C29H27F3N6O |
| molecular weight | 532.56 g/mol | Exact mass | - |
| PSA | 77.200 Ų | logp | 4.6 |
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