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Tyrosine kinase-IN-1

CAS number:705946-27-6    molecular formula:C26H28FN5O

overview

compound introduction

Tyrosine kinase-IN-1是多靶点的酪氨酸激酶抑制剂,抑制 KDR,Flt-1,FGFR1 和 PDGFRα 的 IC50 值分别为4,20,4,2 nM。 Information Tyrosine kinase-IN-1 (XL999) is a multi-targeted tyrosine kinase inhibitor with IC50 of 4 nM, 20 nM, 4 nM, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively.

Specs

Chinese alias-
English aliasGTPL9905 | 2H-Indol-2-one, 5-((1-ethyl-4-piperidinyl)amino)-3-((3-fluorophenyl)(4-methyl-1H-imidazol-2-yl)methylene)-1,3-dihydro-, (3Z)- | SCHEMBL13586874 | BDBM50421033 | EX-A3204 | 2H-Indol-2-one, 5-((1-ethyl-4-piperidinyl)amino)-3-((3-fluorophenyl)(5-m
CAS number705946-27-6molecular formulaC26H28FN5O
molecular weight445.53 g/molExact mass-
PSA73.100 Ųlogp4.400

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