CAS number：1450881-55-6 molecular formula：C21H18ClFN4O4
Information SAR-20347 is a potent inhibitor ofTYK2,JAK1,JAK2andJAK3with IC50 of 0.6 nM, 23 nM, 26 nM and 41 nM, respectively. SAR-20347 inhibits TYK2- and JAK1-mediatedIL-12andIFN-αsignaling. Targets IL-12 ; IFN-α ; TYK2 (Cell-free assay); JAK1 (Cell-free assay); JAK2 (Cell-free assay) 32707,; 0.6 nM; 23 nM; 26 nM
| Chinese alias | - | ||
| English alias | 2-(2-Chloro-6-fluorophenyl)-5-(4-(morpholine-4-carbonyl)phenylamino)oxazole-4-carboxamide | SAR20347 | SAR 20347 | 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide | ||
| CAS number | 1450881-55-6 | molecular formula | C21H18ClFN4O4 |
| molecular weight | 444.84 g/mol | Exact mass | - |
| PSA | 111.000 Ų | logp | 3.500 |
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