compound introduction
Information Solcitinib (GLPG0778, GSK2586184) is an inhibitor ofJAK1with an IC50 of 8-9 nM, and shows 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively. Targets JAK2 ; JAK3 ; TYK2 ; JAK1 ; 8-9 nM
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Solcitinib
CAS number：1206163-45-2 molecular formula：C22H23N5O2
overview
Specs
| Chinese alias | - | ||
| English alias | AS-56075 | A14405 | A892157 | GSK 2586184 | NSC 59989 | SB16965 | GLPG-0778;Solcitinib | MPYACSQFXVMWNO-UHFFFAOYSA-N | VERATRALDEHYDE [FHFI] | Q10395590 | s5917 | SOLCITINIB [WHO-DD] | G154578 | G-154578 | GLPG-0788 | Cyclopropanecarboxamide, N-(5-(4-((3, | ||
| CAS number | 1206163-45-2 | molecular formula | C22H23N5O2 |
| molecular weight | 389.45 g/mol | Exact mass | - |
| PSA | 79.600 Ų | logp | 3.118 |
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