CAS number：2231744-29-7 molecular formula：C41H41N9O8
Information MT-802 MT-802 is a potent PROTAC that induces Bruton's tyrosine kinase (BTK) knockdown. MT-802 recruits BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome. MT-802 has potential for treatment of C481S mutant chronic lymphocytic leukemia (CLL). Targets BTK
| Chinese alias | - | ||
| English alias | Acetamide,2-[2-[2-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]- | ||
| CAS number | 2231744-29-7 | molecular formula | C41H41N9O8 |
| molecular weight | 787.82 g/mol | Exact mass | ≥95% |
| PSA | 213.000 Ų | logp | 2.300 |
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