CAS number：1258292-64-6 molecular formula：C16H13Cl2N3O2
Information GDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor ofTYK2with Ki of 4.8 nM, 83.8 nM, 27.6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively. Targets TYK2 (Cell-free assay); JAK2 (Cell-free assay); JAK1 (Cell-free assay); JAK3 (Cell-free assay) 4.8 nM(Ki); 27.6 nM(Ki); 83.8 nM(Ki); 253 nM(Ki)
| Chinese alias | - | ||
| English alias | Benzamide,2,6-dichloro-N-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]- | ||
| CAS number | 1258292-64-6 | molecular formula | C16H13Cl2N3O2 |
| molecular weight | 350.2 g/mol | Exact mass | ≥99% |
| PSA | 71.100 Ų | logp | 2.900 |
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