CAS number：246512-44-7 molecular formula：C15H23N3O4
Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY-50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity. Form:Solid
| Chinese alias | 吉非替尼杂质 2 | ||
| English alias | Benzamide, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]- | Gefitinib impurity 2 | HY-100663 | I11734 | 2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzamide | HFUBNPPCNQAACT-UHFFFAOYSA-N | Gefitinib Impurity 18 | 2-amino-4-methoxy-5-(3-morpholinopropo | ||
| CAS number | 246512-44-7 | molecular formula | C15H23N3O4 |
| molecular weight | 309.36 g/mol | Exact mass | ≥99% |
| PSA | 100.000 Ų | logp | 0.600 |
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