CAS number：1858291-14-1 molecular formula：C19H22ClN7O3
(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less active. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor ( EGFR ). PF-06459988 has excellent selectivity against EGFR wild-type while possessing a minimally reactive electrophile that reduces the propensity of off-target labeling.
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| CAS number | 1858291-14-1 | molecular formula | C19H22ClN7O3 |
| molecular weight | 431.88 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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