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Ligandrol (LGD-4033)

CAS number:1165910-22-4    molecular formula:C14H12F6N2O

overview

compound introduction

Information Ligandrol (LGD-4033) Ligandrol (LGD-4033, VK-5211) is a novel nonsteroidal, oral selective androgen receptor modulator with high affinity (Ki of ∼1 nM) and selectivity. Targets Androgen Receptor (Cell-free assay) 1 nM(Ki) In vivo In animal models, LGD-4033 has demonstrated anabolic activity in the muscle, anti-resorptive and anabolic activity in bone, and robust selectivity for muscle versus prostate. LGD-4033 is safe and well tolerated at all doses and displays a prolonged elimination half-life (24-36 hours) and linear PK.

Specs

Chinese alias-
English aliasHY-13981 | LIGANDROL [NFLIS-DRUG] | LGD-4033LGD-4033 | LIGANDROL;LGD-4033 | 4-[(2R)-2-[(1R)-2,2,2-TRIFLUORO-1-HYDROXYETHYL]PYRROLIDIN-1-YL]-2-(TRIFLUOROMETHYL)BENZONITRILE | A14346 | VK 5211 [WHO-DD] | Ligandrol | OPSIVAKKLQRWKC-VXGBXAGGSA-N | DTXSID10657
CAS number1165910-22-4molecular formulaC14H12F6N2O
molecular weight338.25 g/molExact mass10mM in DMSO
PSA47.300 Ųlogp3.700

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