CAS number：251310-57-3 molecular formula：C21H20F3N5O4
Thyroid hormone receptorantagonist (1-850) 是一种竞争性、选择性、高亲和力的甲状腺激素受体 (TR) 拮抗剂，拮抗 T3 对 TR 的影响的IC50为 1.5 μM。Thyroid hormone receptorantagonist (1-850) 可阻断 T3 介导的 TRα 和 TRβ 与核受体共激活剂的相互作用。Thyroid hormone receptorantagonist (1-850) 对 RARα 的活性没有影响。
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| CAS number | 251310-57-3 | molecular formula | C21H20F3N5O4 |
| molecular weight | 463.42 g/mol | Exact mass | - |
| PSA | 119.000 Ų | logp | 3.300 |
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