compound introduction
DOV-216,303是有效的 5-羟色胺、去甲肾上腺素、多巴胺再摄取的三重抑制剂，其对 hSERT、hNET 和 hDAT 的 IC50 值分别为 14 nM，20 nM和78 nM。在嗅球切除大鼠模型中，可增加前额皮质中单胺的释放及具有抗抑郁的作用。
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1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane
CAS number：66504-40-3 molecular formula：C11H11Cl2N
overview
Specs
| Chinese alias | - | ||
| English alias | DOV-216,303 | ||
| CAS number | 66504-40-3 | molecular formula | C11H11Cl2N |
| molecular weight | 228.12 g/mol | Exact mass | ≥97% |
| PSA | 12.000 Ų | logp | 3.000 |
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