compound introduction
Neurokinin-1 Receptor Antagonist 是一种三唑基酰胺化合物，可作为P特异神经激肽受体NK1的高亲和力（K | i | = 251 nM）拮抗剂。显示与物质P竞争在整个CHO细胞上与NK1的结合。与CP-96345具有相似的药效基团特征，但在结构上与CP-96345不同。 Neurokinin-1 Receptor Antagonist is a triazolyl-amide compound that acts as a high-affinity (K|i|= 251 nM) antagonist for NK1, the substance P-specific neurokinin receptor. Shown to compete with substance P binding to NK1 on whole CHO cells. Exhibits similar pharmacophore features as, but is structurally distinct from, CP-96345.
