Protein Function: (C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.
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Recombinant Human CXCL10/IP-10 Protein
CAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | 重组人CXCL10/IP-10蛋白 | 重组人 CXCL10/IP-10 蛋白 | ||
| English alias | chemokine (C-X-C motif) ligand 10 | CRG2 | CRG-2 | CXCL10 | gIP-10 | IFI10 | INP10 | IP-10 | mob-1 | SCYB10 | C7 | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无载体 |
| PSA | - | logp | - |
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