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3-(2,4-Dichlorophenyl)-4-(1H-imidazol-1-yl)butyl 4-fluorophenyl ether

CAS number:64009-84-3    molecular formula:C19H17Cl2FN2O

overview

compound introduction

IMB-301 是一种特异性的HIV-1复制抑制剂,能与hA3G (human APOBEC3G)结合,阻断 hA3G-Vif 相互作用,抑制 Vif 介导的 hA3G 降解。IMB-301 抑制 H9 细胞中HIV-1的复制 (IC50=8.63 uM)。人 APOBEC3G 是一种抑制HIV-1复制的限制因子。

Specs

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CAS number64009-84-3molecular formulaC19H17Cl2FN2O
molecular weight379.300 g/molExact mass≥99%
PSA27.100 Ųlogp5.100

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