IMB-301 是一种特异性的HIV-1复制抑制剂,能与hA3G (human APOBEC3G)结合,阻断 hA3G-Vif 相互作用,抑制 Vif 介导的 hA3G 降解。IMB-301 抑制 H9 细胞中HIV-1的复制 (IC50=8.63 uM)。人 APOBEC3G 是一种抑制HIV-1复制的限制因子。
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3-(2,4-Dichlorophenyl)-4-(1H-imidazol-1-yl)butyl 4-fluorophenyl ether
CAS number:64009-84-3 molecular formula:C19H17Cl2FN2O
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 64009-84-3 | molecular formula | C19H17Cl2FN2O |
| molecular weight | 379.300 g/mol | Exact mass | ≥99% |
| PSA | 27.100 Ų | logp | 5.100 |
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