compound introduction
SD 0006 (SD-06) 是口服有效的、选择性的、ATP竞争性的、有效的 p38α MAPK 的二芳基吡唑抑制剂，其IC50 值为 110 nM。
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SD-06
CAS number：271576-80-8 molecular formula：C20H20ClN5O2
overview
Specs
| Chinese alias | - | ||
| English alias | Ethanone, 1-(4-(5-(4-chlorophenyl)-4-(4-pyrimidinyl)-1H-pyrazol-3-yl)-1-piperidinyl)-2-hydroxy- | HY-11087 | J-503197 | 1-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyrazol-5-yl)piperidin-1-yl)-2-hydroxyethanone | n-(2-hydroxyacetyl)-5-(4-piperidyl)-4-( | ||
| CAS number | 271576-80-8 | molecular formula | C20H20ClN5O2 |
| molecular weight | 397.87 g/mol | Exact mass | 10mM in DMSO |
| PSA | 95.000 Ų | logp | 1.9 |
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