compound introduction
Tepotinib (EMD 1214063, MSC2156119) 是一种有效的，选择性的c-Met抑制剂，IC50为4 nM，作用于c-Met比作用于IRAK4， TrkA， Axl， IRAK1和Mer选择性高200倍以上。Tepotinib 可诱导自噬。Phase 1。
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EMD 1214063
CAS number：1100598-32-0 molecular formula：C29H28N6O2
overview
Specs
| Chinese alias | 特泊替尼 | ||
| English alias | Tepotinib | MSC2156119 | Benzonitrile, 3-[1,6-dihydro-1-[[3-[5-[(1-methyl-4-piperidinyl)methoxy]-2-pyrimidinyl]phenyl]methyl]-6-oxo-3-pyridazinyl]- | TEPOTINIB [WHO-DD] | Tepotinib(EMD-1214063) | MSC2156119J | AHYMHWXQRWRBKT-UHFFFAOYSA-N | compound 22 [PM | ||
| CAS number | 1100598-32-0 | molecular formula | C29H28N6O2 |
| molecular weight | 492.57 g/mol | Exact mass | - |
| PSA | 94.700 Ų | logp | 3.4 |
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