CAS number：1224844-38-5 molecular formula：C15H15N7O
INK 128是高活性mTOR抑制剂，IC50为1 nM，比对其它I型PI3K亚型的抑制性高200倍。A potent and selective TORC1/2 inhibitor INK 128 (MLN0128) is a potent and selective mTOR inhibitor with IC50 of 1 nM in cell-free assays; >200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin). A potent and selective TORC1/2 inhibitor
| Chinese alias | - | ||
| English alias | 2-Benzoxazolamine, 5-(4-amino-1-(1-methylethyl)-1H-pyrazolo(3,4-d)pyrimidin-3-yl)- | 3-(2-aminobenzo[d]oxazol-5-yl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 5-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine | J-00481 | ||
| CAS number | 1224844-38-5 | molecular formula | C15H15N7O |
| molecular weight | 309.33 g/mol | Exact mass | - |
| PSA | 122.000 Ų | logp | 1.7 |
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