CAS number：500579-04-4 molecular formula：C27H35N5
GANT61 (NSC 136476)是一种GLI1及GLI2诱导的转录抑制剂，抑制hedgehog，在表达GLI1的HEK293T细胞中IC50为5 μM，选择性作用于其他通路，如TNF和糖皮质激素受体基因的转录。GANT61在LX-2细胞中可诱导凋亡并激活保护性自噬。 GANT 61 是靶向Hedgehog/GLi通路的 Gli1 和 Gli2 抑制剂。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
| Chinese alias | 2,2'-[[二氢-2-(4-吡啶基)-1,3-(2H,4H)-嘧啶二基]双(亚甲基)]双[N,N-二甲基苯胺 | 2,2'-[[二氢-2-(4-吡啶基)-1,3(2H,4H)-嘧啶二基]双(亚甲基)]双(N,N-二甲基苯胺) | ||
| English alias | NSC 136476 | GANT61 | NCIStruc1_001747 | NCGC00014352-03 | GANT61(NSC 136476) | CHEBI:94276 | DTXSID50329591 | GANT 61(NSC 136476) | 2,2''-(2-(pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene)bis(N,N-dimethylaniline) | 2,2'-(2-(pyridin-4-yl)di | ||
| CAS number | 500579-04-4 | molecular formula | C27H35N5 |
| molecular weight | 429.61 g/mol | Exact mass | ≥98% |
| PSA | 25.900 Ų | logp | 4.200 |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
