compound introduction
Thalidomide-O-C8-COOH 是一种基于 Thalidomide 的，可募集 CRBN 蛋白的Cereblon配体。Thalidomide-O-C8-COOH 可通过 linker 与靶蛋白配体连接，形成 PROTAC 分子。
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Thalidomide 4'-ether-alkylC8-acid
CAS number：2225148-51-4 molecular formula：C22H26N2O7
overview
Specs
| Chinese alias | 9-[[2-(2,6-二氧代-3-哌啶基)-2,3-二氢-1,3-二氧代-1H-异吲哚-4-基]氧基]壬酸 | ||
| English alias | 9-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]nonanoic acid | Thalidomide-O-C8-COOH | ||
| CAS number | 2225148-51-4 | molecular formula | C22H26N2O7 |
| molecular weight | 430.46 g/mol | Exact mass | ≥95%(HPLC) |
| PSA | 130.000 Ų | logp | 2.500 |
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