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MW-150

CAS number:1628502-91-9    molecular formula:C24H23N5

overview

compound introduction

Information MW150 (MW01-18-150SRM) is a selective, CNS-penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia.

Specs

Chinese alias-
English alias6-(4-Methyl-piperazin-1-yl)-(2-naphthalen-2-yl)-4-pyridin-4-ylpyridazine | 6-(4-methyl-1-piperazinyl)-3-(2-naphthalenyl)-4-(4-pyridinyl)-pyridazine | 6-(4-Methylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)pyridazine | MS-26255 | MW 150 | BDBM50537
CAS number1628502-91-9molecular formulaC24H23N5
molecular weight381.47 g/molExact mass-
PSA45.200 Ųlogp3.600

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