Information MW150 (MW01-18-150SRM) is a selective, CNS-penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia.
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MW-150
CAS number:1628502-91-9 molecular formula:C24H23N5
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Specs
| Chinese alias | - | ||
| English alias | 6-(4-Methyl-piperazin-1-yl)-(2-naphthalen-2-yl)-4-pyridin-4-ylpyridazine | 6-(4-methyl-1-piperazinyl)-3-(2-naphthalenyl)-4-(4-pyridinyl)-pyridazine | 6-(4-Methylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)pyridazine | MS-26255 | MW 150 | BDBM50537 | ||
| CAS number | 1628502-91-9 | molecular formula | C24H23N5 |
| molecular weight | 381.47 g/mol | Exact mass | - |
| PSA | 45.200 Ų | logp | 3.600 |
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