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Dasatinib hydrochloride

CAS number:854001-07-3    molecular formula:C22H27Cl2N7O2S

overview

compound introduction

Information Dasatinib hydrochloride (BMS-354825) is the hydrochloride salt form of dasatinib, an inhibitor that targetsAbl, Src and c-Kit, with IC50 of Targets Abl (Cell-free assay); Src (Cell-free assay); c-Kit (D816V) (Cell-free assay); c-Kit (wt) (Cell-free assay) 0.6 nM; 0.8 nM; 37 nM; 79 nM

Specs

Chinese alias-
English aliasBMS-354825 HCl5-​Thiazolecarboxamide,N-​(2-​chloro-​6-​methylphenyl)​-​2-​[[6-​[4-​(2-​hydroxyethyl)​-​1-​piperazinyl]​-​2-​methyl-​4-​pyrimidinyl]​amino]​-​,hydrochloride (1:1)
CAS number854001-07-3molecular formulaC22H27Cl2N7O2S
molecular weight524.47 g/molExact mass10mM in DMSO
PSA135.000 Ųlogp3.821

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