CAS number：856243-80-6 molecular formula：C19H18BrN3O
Degrasyn (WP1130)是一种选择性的去泛素化酶(DUB: USP5， UCH-L1， USP9x， USP14， UCH37)抑制剂，也抑制Bcr/Abl，也是一种JAK2传感器(不影响20S蛋白酶体)和转录激活剂(STAT)。 Degrasyn (WP1130) is a selective deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor and also suppresses Bcr/Abl, also a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT). A selective deubiquitinase inhibitor and also suppresses Bcr/Abl.
| Chinese alias | 德格拉辛 (WP1130) | ||
| English alias | WP1130 | WP-1130 | Degrasyn (WP1130) | SCHEMBL1317674 | SCHEMBL882501 | DTXSID50459281 | s11144 | WP1130(Degrasyn) | Z2312381828 | AMY20034 | (S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide | EX-A2048 | AC-28415 | BDBM50437695 | HY-13264 | ||
| CAS number | 856243-80-6 | molecular formula | C19H18BrN3O |
| molecular weight | 384.27 g/mol | Exact mass | ≥98% |
| PSA | 65.800 Ų | logp | 4.300 |
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