compound introduction
MRT67307 是 IKKε 和 TBK-1 的双抑制剂，IC50 分别为 160 和 19 nM。MRT67307 也可抑制 ULK1 和 ULK2，IC50 分别为 45 和 38 nM。MRT67307 还抑制细胞自噬 (autophagy)。 产品应用： MRT67307 已用于研究其对 LPS（脂多糖）诱导溶酶体管状结构的影响。
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
MRT67307
CAS number：1190378-57-4 molecular formula：C26H36N6O2
overview
Specs
| Chinese alias | - | ||
| English alias | BS-14599 | NCGC00163978-01 | AKOS030526302 | N-{3-[(5-Cyclopropyl-2-{[3-(Morpholin-4-Ylmethyl)phenyl]amino}pyrimidin-4-Yl)amino]propyl}cyclobutanecarboxamide | N-{3-[(5-Cyclopropyl-2-{3-[(morpholin-4-yl)methyl]anilino}pyrimidin-4-yl)amino]propyl}cyclobuta | ||
| CAS number | 1190378-57-4 | molecular formula | C26H36N6O2 |
| molecular weight | 464.6 g/mol | Exact mass | - |
| PSA | 91.400 Ų | logp | 4.000 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
