LC3-mHTT-IN-AN1 (Compound AN1) 是一种 mHTT-LC3 连接化合物,LC3-mHTT-IN-AN1 与突变型亨廷顿蛋白 (mHTT) 和 LC3B 相互作用,但不与 wtHTT 或无关的对照蛋白相互作用。LC3-mHTT-IN-AN1 以等位基因选择性的方式降低了亨廷顿病 (HD) 小鼠神经元中mHTT水平。
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LC3-mHTT-IN-AN1
CAS number:486443-73-6 molecular formula:C15H9Br2NO3
overview
compound introduction
Specs
| Chinese alias | (3Z)-5-溴-3-(3-溴-4,5-二羟基亚苄基)-1,3-二氢-2H-吲哚-2-酮 | ||
| English alias | - | ||
| CAS number | 486443-73-6 | molecular formula | C15H9Br2NO3 |
| molecular weight | 411.04 g/mol | Exact mass | ≥97% |
| PSA | 69.600 Ų | logp | 3.600 |
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