CAS number：64567-60-8 molecular formula：C13H10N2O5
Thalidomide-5-OH 是基于 Thalidomide 的的cereblon 配体，可用于募集CRBN 蛋白。它能够利用 linker 与靶蛋白配体连接，得到 PROTAC 分子。 Thalidomide-5-OH is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
| Chinese alias | 4-羟基沙利度胺 | ||
| English alias | (+/-)-Hydroxythalidomide | 2-(2,6-dioxopiperidin-3-yl)-5-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione | alpha-N-(4-Hydroxyphthalimido)-glutarimide | 5-hydroxythalidomide | CHEBI:168639 | 2-Piperidinoethyl bicyclohexan-1-carboxylat [IUPAC] | TQP0426 | 5-HYDR | ||
| CAS number | 64567-60-8 | molecular formula | C13H10N2O5 |
| molecular weight | 274.23 g/mol | Exact mass | ≥95% |
| PSA | 104.000 Ų | logp | 0.000 |
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