compound introduction
Sunitinib-d 10 is a deuterium labeled Sunitinib. Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ , respectively. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation. Form:Solid IC50& Target:VEGFR2 80 nM (IC 50 ) PDGFRβ 2 nM (IC 50 )
