CAS number：2055015-61-5 molecular formula：C16H16F3N3O5S
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC 50 of 11.1 nM In Vitro GLPG2451 has an EC 50 value of 675 nM and an efficacy level of 147% of that of VX770 in G551D/F508del cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Cystic fibrosis transmembrane conductance regulator
| Chinese alias | - | ||
| English alias | AKOS040740795 | 2055015-61-5 | 3-amino-N-[(2S)-2-hydroxypropyl]-5-[4-(trifluoromethoxy)phenyl]sulfonylpyridine-2-carboxamide | SCHEMBL18279096 | BDBM50566257 | MS-27341 | UNII-W94ID4MZ81 | 2-Pyridinecarboxamide, 3-amino-N-((2S)-2-hydroxypropyl)-5-((4-(tri | ||
| CAS number | 2055015-61-5 | molecular formula | C16H16F3N3O5S |
| molecular weight | 419.38 g/mol | Exact mass | ≥99% |
| PSA | 140.000 Ų | logp | 2.100 |
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