K67 specifically inhibits the interaction between Keap1 and S 349 -phosphorylated p62. K67 prevents p-p62 from blocking the binding of Keap1 and Nrf2. K67 effectively inhibits the proliferation of HCC cultures with high cellular S 351 -phosphorylated p62 by restoring the ubiquitination and degradation of Nrf2 driven by Keap1. Form:Solid
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K67
CAS number:2046250-48-8 molecular formula:C29H30N2O7S2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2046250-48-8 | molecular formula | C29H30N2O7S2 |
| molecular weight | 582.69 g/mol | Exact mass | ≥98% |
| PSA | 145.000 Ų | logp | 4.500 |
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