CAS number：681136-29-8 molecular formula：C19H19N5OS
JNJ-1661010是一种有效的，选择性的FAAH抑制剂，IC50分别为10 nM(大鼠)和12 nM (人类)，作用于FAAH-1比作用于FAAH-2选择性高100倍以上。A selective and reversible inhibitor of fatty acid amide hydrolase (FAAH). JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2. A selective and reversible inhibitor of fatty acid amide hydrolase (FAAH).
| Chinese alias | - | ||
| English alias | AKOS024457512 | 1-Piperazinecarboxamide, N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)- | N1-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide | HMS3651L15 | N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide | Oprea1_746619 | ||
| CAS number | 681136-29-8 | molecular formula | C19H19N5OS |
| molecular weight | 365.45 g/mol | Exact mass | - |
| PSA | 89.600 Ų | logp | 3.500 |
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