MG-115 是一种有效和可逆的蛋白酶体抑制剂,对 20S 和 26S 蛋白酶体的 Ki 值分别为 21 nM 和 35 nM。MG-115 特异性抑制蛋白酶体的胰凝乳蛋白酶样活性,诱导 p53 依赖性细胞凋亡。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
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MG-115
CAS number:133407-86-0 molecular formula:C25H39N3O5
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxopentan-2-yl]amino]pentan-2-yl]amino]-1-oxopentan-2-yl]carbamic acid (phenylmethyl) ester | NCGC00345815-01 | HY-108552 | SCHEMBL2140161 | carbobenzoxy-leucyl-leucyl-norvalinal | Cbz-Leu-Leu-norvalinal | ||
| CAS number | 133407-86-0 | molecular formula | C25H39N3O5 |
| molecular weight | 461.59 g/mol | Exact mass | - |
| PSA | 114.000 Ų | logp | 4.400 |
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