Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation.
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Recombinant Human Nanog Protein
CAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | 重组人Nanog蛋白 | 重组人类 Nanog 蛋白 | ||
| English alias | hNanog | Homeobox transcription factor Nanog | FLJ12581 | FLJ40451 | hNanog | homeobox protein NANOG | Homeobox transcription factor Nanog | homeobox transcription factor Nanog-delta 48 | Nanog homeobox | Nanog | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无载体 |
| PSA | - | logp | - |
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