CAS number：49763-96-4 molecular formula：C14H18O3
Stiripentol (STP) 是一种抗惊厥剂，其可以抑制由 CYP3A4 (非竞争性) 和 CYP2C19 (竞争性地) 介导的 CLB 向 N-desmethylclobazam (NCLB) 的 N-去甲基化，其 Ki 值分别为 1.59±0.07 和 0.516±0.065 μM，IC50 值分别为 1.58 和 3.29 μM。 Stiripentol (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediatated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59±0.07 and 0.516±0.065 μM and IC50 of 1.58 and 3.29 μM, respectively.
| Chinese alias | 1-(1,3-苯并二氧-5-基)-4,4-二甲基-1-戊烯-3-醇 | 4,4-二甲基-1-(3,4-亚甲基二氧苯基)-1-戊烯-3-醇 | ||
| English alias | 1-(Benzo[d][1,3]dioxol-5-yl)-4,4-dimethylpent-1-en-3-ol | BCX2600; BCX-2600; BCX 2600 | SCHEMBL216436 | s5266 | 5-19-02-00640 (Beilstein Handbook Reference) | BS-16863 | Estiripentol (INN-Spanish) | C.I. Reducing Agent 6 | Estiripentol | R02XOT8V8I | Stir | ||
| CAS number | 49763-96-4 | molecular formula | C14H18O3 |
| molecular weight | 234.3 g/mol | Exact mass | - |
| PSA | 38.700 Ų | logp | 3.600 |
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