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N-butyryl-L-Homoserine lactone

CAS number:67605-85-0    molecular formula:C8H13NO3

overview

compound introduction

N-丁酰基-L-高丝氨酸内酯,群体感应是细菌用于控制响应于细胞密度增加的基因表达的调节系统。通过淬灭群体感应系统来控制细菌感染是一个有前途的研究领域。特定靶基因(例如属于LuxIR蛋白质家族的转录调节因子)的表达通过可扩散的酰基高丝氨酸内酯(AHL)分子的合成来协调。N-丁酰-L-高丝氨酸内酯是一种小的可扩散信号分子,参与群体感应,控制基因表达和细胞代谢。该分子的各种应用包括一般的毒力调节,感染预防和生物膜形成。 N-butyryl-L-Homoserine lactone, quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

Specs

Chinese aliasN-[(3S)-四氢-2-氧代-3-呋喃基]丁酰胺
English aliasN-(butyryl)-L-homoserine lactone | C4-HSL | SR-01000946805 | C4-HSL;N-Butyryl-L-homoserine lactone | N-[(3s)-2-Oxotetrahydrofuran-3-Yl]butanamide | PAI-1-2 | DTXSID30435962 | SB84058 | SY038520 | N-[(3S)-TETRAHYDRO-2-OXO-3-FURANYL]BUTANAMIDE | SCHEMBL1319
CAS number67605-85-0molecular formulaC8H13NO3
molecular weight171.19 g/molExact mass10mM in DMSO
PSA55.400 Ųlogp0.500

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