PROTAC BRD4 Degrader-10 (compound 8b) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC 50 of 1.3 nM and 18 nM, respectively. Form:Solid
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PROTAC BRD4 Degrader-10
CAS number:2417370-49-9 molecular formula:C59H71F2N9O15S4
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| Chinese alias | PROTAC BRD4 降解剂-10 | ||
| English alias | - | ||
| CAS number | 2417370-49-9 | molecular formula | C59H71F2N9O15S4 |
| molecular weight | 1312.50 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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